Firmware You need to be logged in Login or register a new account , to access this content. Linking actin dynamics and gene transcription to drive cellular motile functions. VASP is a processive actin polymerase that requires monomeric actin for barbed end association. A requirement for Mena, an actin regulator, in local mRNA translation in developing neurons. The online version of this article
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Cellular growth and survival are mediated by beta 1 integrins in normal human breast epithelium but not in breast carcinoma.
The gene undergoes a splicing process generating multiple tissue-specific isoforms [ 12 ]. Vsica used are reported in Supplementary Material and Methods. Mechanotransduction and extracellular matrix homeostasis.
Densitometric quantitation of antibody immunoreactivity was determined by Image J 1. Ready to buy Axis products are available through our global partner network.
National Center for Biotechnology InformationU. Moreover, among the significantly reduced secreted proteins we found the colony-stimulating factor 1 CSF1in agreement with previous data in MTLn3 mammary tumors reporting that increased MENA 11a expression correlates with decreased expression of CSF1 [ 42 ].
Camera settings are optimized to produce video visc high-color fidelity in studio environments.
Published online Jun Integrin signaling and lung cancer. To view a copy of this license, visit http: Integrin activation is coordinated by actin cytoskeleton dynamics [ 51 ]. Recommended Spare parts All. Integration with other systems CamStreamer — Stream live video 1.
All the analyses were performed with SPSS statistical software version Integrity checksum Checksums are used to ensure the integrity of a file after it has been downloaded from a server to a client device. These authors contributed equally: Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells.
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Gertler F, Condeelis J. Axiz one of the major streaming platforms to stream or record live video 3. Evaluation of the immunohistochemistry results was performed independently by two investigators MM and PV blinded to patient data.
Support Center Support Center. Linking actin dynamics and gene transcription to drive cellular motile functions.
In fact, our gain and loss of function experiments Fig. Nat Rev Mol Cell Biol.
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In primary tumors high hMENA 11a correlates with low stromal fibronectin and a favorable clinical outcome of early node-negative non-small-cell lung cancer patients. Details regarding materials and cell lines and cultures and information relative to patients and tissue specimens can be found in the Supplementary Materials and Methods. In contrast, hybMENA 11a -positive tumors express essentially a low FN1 level in the stroma, in agreement with the proteomic data obtained for cancer cell lines.
Author information Article notes Copyright and License information Disclaimer. Their mechanisms of action have remained unclear. Here we report two major findings: Francesca Di Modugno and Sheila Spada. The New Orleans Real Time Crime Center integrates Axis cameras to play a critical role in giving first responders immediate incident awareness. Supplementary Figure Legends 26K, docx.